Cardiometabolic Multimorbidity

Cardiometabolic Multimorbidity and Outcomes

  • Our team examined the association between cardiometabolic diseases (CMDs) and depression among middle-aged and older Chinese individuals and found that the presence of multiple CMDs may elevate the risk of depressive symptoms. The study, which utilized data from over 18,000 participants in the China Health and Retirement Longitudinal Study, revealed that stroke, heart disease, and diabetes individually and cumulatively increased the likelihood of depression. Interestingly, hypertension and dyslipidemia were only associated with depression when present alongside other CMDs. These findings underscore the importance of integrated mental health care in managing multiple CMDs.

Cardiometabolic Multimorbidity Transition

  • Our group described the transitions of cardiometabolic disease, multimorbidity, and mortality utilizing multi-state Markov models among 17,250 older patients with hypertension. In addition, we investigated the literature related to multimorbidity patterns/clusters and the network analysis in the past five years; gained expertise in the complex network and overlapping community detection.
Yan Luo
Yan Luo
PhD candidate in Data Science

My research focuses on using machine learning approaches to identify social determinants and biological markers of diseases and aging, aiming to improve population health.